Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11288125 | 1.00 | ALDH1A1 (0.57) | ALDH1A1LMNAKMT2APOLBL3MBTL1 | |
| SCHEMBL11276813 | 0.85 | MEN1 (0.53) | KMT2APOLBL3MBTL1MEN1MAPT | |
| SCHEMBL11276816 | 0.85 | MEN1 (0.53) | KMT2APOLBL3MBTL1MEN1MAPT | |
| SCHEMBL11282683 | 0.77 | ALDH1A1 (0.61) | ALDH1A1LMNAKMT2APOLBL3MBTL1 | |
| SCHEMBL11282687 | 0.77 | ALDH1A1 (0.61) | ALDH1A1LMNAKMT2APOLBL3MBTL1 | |
| SCHEMBL11287920 | 0.76 | CFD (0.41) | KMT2AL3MBTL1MEN1MAPT | |
| SCHEMBL11277846 | 0.75 | GPR183 (0.50) | MAPT | |
| SCHEMBL11277852 | 0.75 | GPR183 (0.50) | MAPT | |
| SCHEMBL11282141 | 0.74 | MAOB (0.58) | ALDH1A1LMNAKMT2APOLBMAPK1 | |
| SCHEMBL11282147 | 0.74 | MAOB (0.58) | ALDH1A1LMNAKMT2APOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4352928-A | ANTIINFLAMMATORY, HYPOGLYCEMIC, ANTICOAGULANT, ANOREXIGENIC, SEROTONIN EFFEC | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-10-05 | — | — | US | disclosed |
| EP-0022481-A1 | 5,6-Alkylenepyrimidine derivatives, processes for preparing the same and pharmaceutical compositions | Mitsubishi Yuka Pharmaceutical Co., Ltd. (JP) | 1981-01-21 | — | — | EP | disclosed |