Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | USP14 | P54578 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11284814 | 0.99 | ALDH1A1 (0.47) | ALDH1A1MAPTUSP14GAAKMT2A | |
| SCHEMBL11283956 | 0.77 | MAPT (0.54) | ALDH1A1MAPTGAAKMT2AKDM4E | |
| SCHEMBL11277750 | 0.77 | MAPT (0.54) | ALDH1A1MAPTGAAKMT2AKDM4E | |
| SCHEMBL11272460 | 0.75 | ALDH1A1 (0.55) | ALDH1A1MAPTGAAKMT2AKDM4E | |
| SCHEMBL10749731 | 0.73 | LMNA (0.62) | ALDH1A1GAATSHRSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL11268933 | 0.73 | HRH3 (0.62) | ALDH1A1KMT2AMEN1HRH3 | |
| SCHEMBL11275594 | 0.73 | HPGDS (0.50) | ALDH1A1MAPTGAAKMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL11279012 | 0.72 | HPGDS (0.49) | ALDH1A1MAPTGAAKMT2AKDM4E | |
| SCHEMBL11268789 | 0.72 | MAPT (0.48) | ALDH1A1MAPTGAAKMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL11273763 | 0.72 | L3MBTL1 (0.46) | ALDH1A1MAPTKMT2AKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327022-A | Heterocyclic alkyl naphthols | STERLING DRUG INC. (US) | 1982-04-27 | — | — | US | disclosed |
| US-4169108-A | 5(OR 6)-[(Substituted-amino)alkyl]-2,3-naphthalenediols | STERLING DRUG INC. (US) | 1979-09-25 | — | — | US | disclosed |