Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11283415 | 0.96 | HDAC3 (0.43) | HDAC3HDAC1HDAC2SLC2A1MRGPRX4 | |
| SCHEMBL11277117 | 0.89 | FFAR1 (0.46) | PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL11208063 | 0.83 | FFAR1 (0.43) | SLC2A1HRH3SIGMAR1 | |
| SCHEMBL11276905 | 0.82 | MRGPRX4 (0.40) | MRGPRX4MMP1MMP2MMP9MMP14 | |
| SCHEMBL11211662 | 0.82 | SIGMAR1 (0.48) | HDAC3HDAC1HDAC2SLC2A1SIGMAR1 | |
| SCHEMBL11211010 | 0.77 | HDAC3 (0.48) | HDAC3HDAC1HDAC2SIGMAR1 | |
| SCHEMBL11279957 | 0.74 | RAB9A (0.44) | MRGPRX4MMP1MMP2MMP9MMP14 | |
| SCHEMBL14163891 | 0.74 | RXRA (0.56) | MRGPRX4MMP1MMP2MMP9MMP14 | |
| SCHEMBL11208145 | 0.73 | FFAR1 (0.46) | HRH3 | |
| SCHEMBL11209448 | 0.71 | BCHE (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051196-A1 | 4-Benzyloxy-alpha-trichloromethylbenzyl amines, process for their preparation, pesticidal compositions containing them, their preparation and use | BAYER AG (DE) | 1982-05-12 | — | — | EP | disclosed |