Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A3 | O75751 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | BLM | P54132 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11526874 | 0.90 | SLC22A3 (0.56) | SLC22A3ADRB2MAPTKDM4ETDP1 | |
| SCHEMBL11284068 | 0.86 | ADRB3 (0.51) | SLC22A3ADRB2MAPTKDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL11287403 | 0.82 | SLC22A3 (0.46) | SLC22A3ADRB2MAPTKDM4ETDP1 | |
| SCHEMBL11277192 | 0.82 | MAPT (0.39) | SLC22A3ADRB2MAPTPOLBMAPK1 | |
| SCHEMBL11289538 | 0.80 | ADRB2 (0.59) | SLC22A3ADRB2MAPTKDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL11289535 | 0.79 | ADRB2 (0.60) | SLC22A3ADRB2MAPTKDM4ETDP1 | |
| Trifluoroacetic Acid SCHEMBL11282524 | 0.78 | LMNA (0.41) | ADRB2HIF1ALMNACYP3A4CYP2D6 | |
| SCHEMBL11290751 | 0.78 | SLC22A3 (0.41) | SLC22A3ADRB2MAPTKDM4ETDP1 | |
| SCHEMBL11525219 | 0.77 | HIF1A (0.51) | SLC22A3ADRB2MAPTKDM4ETDP1 | |
| SCHEMBL10897411 | 0.77 | ADRB2 (0.48) | ADRB2MAPTTDP1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |