Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11267250 | 0.84 | HTT (0.53) | KDM4ETTRALDH1A1HPGDHSD17B10 | |
| SCHEMBL11280577 | 0.81 | AKR1B1 (0.43) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL11270952 | 0.78 | NPC1 (0.43) | THRATHRBPTGER4KDM4EALDH1A1 | |
| SCHEMBL1037140 | 0.75 | PTGER4 (0.52) | PTGER4KDM4EDAOALDH1A1 | |
| SCHEMBL14818675 | 0.73 | SMN1; SMN2 (0.37) | PTGER4KDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL3217997 | 0.73 | SMN1; SMN2 (0.55) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL1171093 | 0.71 | DAO (0.50) | KDM4EIDH1DAO | |
| SCHEMBL10328613 | 0.71 | ALDH1A1 (0.40) | PTGER4KDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL6402963 | 0.70 | MRGPRX4 (0.48) | PTGER4KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11265196 | 0.70 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4364956-A | ASTHMA | LILLY INDUSTRIES LIMITED (GB) | 1982-12-21 | — | — | US | disclosed |