Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | SELE | P16581 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11261990 | 0.84 | MAOB (0.44) | ALDH1A1HPGDNPSR1MAPTKDM4E | |
| SCHEMBL11270952 | 0.83 | NPC1 (0.43) | ALDH1A1POLBAPOBEC3ACTDSP1APOBEC3G | |
| SCHEMBL11282494 | 0.74 | CASP1 (0.41) | ALDH1A1SMN1; SMN2MAPTTDP1L3MBTL1 | |
| SCHEMBL11266671 | 0.74 | SRD5A2 (0.51) | ALDH1A1NR4A2RXRARXRBSMN1; SMN2 | |
| SCHEMBL3217997 | 0.73 | SMN1; SMN2 (0.55) | ALDH1A1HPGDNPSR1SMN1; SMN2MAPT | |
| SCHEMBL11267250 | 0.72 | HTT (0.53) | ALDH1A1HPGDRXRASMN1; SMN2TDP1 | |
| SCHEMBL10328613 | 0.71 | ALDH1A1 (0.40) | ALDH1A1HPGDRXRARXRBSMN1; SMN2 | |
| SCHEMBL11277288 | 0.70 | THRA (0.39) | ALDH1A1HPGDTDP1KDM4E | |
| SCHEMBL2448070 | 0.70 | RXRB (0.39) | NR4A2RXRARXRBTDP1NR4A1 | |
| SCHEMBL31203341 | 0.70 | KDM4E (0.42) | ALDH1A1HPGDSMN1; SMN2MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4364956-A | ASTHMA | LILLY INDUSTRIES LIMITED (GB) | 1982-12-21 | — | — | US | disclosed |