Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | BAX | Q07812 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PCNA | P12004 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11265196 | 0.83 | ALDH1A1 (0.42) | NPC1RAB9APOLBAPOBEC3ACTDSP1 | |
| SCHEMBL11271259 | 0.81 | AKR1B1 (0.50) | NPC1RAB9AMEN1KMT2AAKR1B1 | |
| SCHEMBL11282494 | 0.79 | CASP1 (0.41) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL11277288 | 0.78 | THRA (0.39) | PTGER4THRATHRBKDM4EALDH1A1 | |
| SCHEMBL3217997 | 0.74 | SMN1; SMN2 (0.55) | RAB9AKDM4EALDH1A1 | |
| SCHEMBL14818675 | 0.74 | SMN1; SMN2 (0.37) | NPC1RAB9AKMT2APTGER4AKR1B1 | |
| SCHEMBL11267250 | 0.74 | HTT (0.53) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL9356623 | 0.73 | RAB9A (0.52) | NPC1RAB9AMEN1KMT2APTGER4 | |
| SCHEMBL1037140 | 0.73 | PTGER4 (0.52) | NPC1RAB9AMEN1KMT2APTGER4 | |
| SCHEMBL10328539 | 0.72 | PTGER4 (0.49) | NPC1RAB9AMEN1KMT2APTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4364956-A | ASTHMA | LILLY INDUSTRIES LIMITED (GB) | 1982-12-21 | — | — | US | disclosed |