Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278088 | 0.87 | PTGS1 (0.65) | POLBALDH1A1SMN1; SMN2PTGS1AKR1C3 | |
| SCHEMBL11271316 | 0.85 | KMT2A (0.55) | POLBSMN1; SMN2PTGS1AKR1C3AKR1C2 | |
| SCHEMBL25024046 | 0.81 | L3MBTL1 (0.53) | L3MBTL1POLBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL4589826 | 0.80 | PTGS1 (0.73) | L3MBTL1POLBALDH1A1SMN1; SMN2PTGS1 | |
| SCHEMBL11275576 | 0.79 | KMT2A (0.67) | L3MBTL1POLBRXFP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11281357 | 0.78 | PTGS1 (0.53) | ALDH1A1SMN1; SMN2PTGS1AKR1C3AKR1C2 | |
| SCHEMBL2450845 | 0.78 | HTT (0.71) | ALDH1A1SMN1; SMN2KMT2AMEN1EPHX2 | |
| SCHEMBL8535521 | 0.77 | HSD17B10 (0.57) | L3MBTL1POLBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL11273025 | 0.77 | PTGS1 (0.48) | RXFP1ALDH1A1SMN1; SMN2PTGS1AKR1C3 | |
| SCHEMBL11283789 | 0.76 | XDH (0.57) | L3MBTL1POLBSMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327022-A | Heterocyclic alkyl naphthols | STERLING DRUG INC. (US) | 1982-04-27 | — | — | US | disclosed |
| US-4169108-A | 5(OR 6)-[(Substituted-amino)alkyl]-2,3-naphthalenediols | STERLING DRUG INC. (US) | 1979-09-25 | — | — | US | disclosed |