Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ACACB | O00763 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19664385 | 0.92 | KMT2A (0.43) | MAPTACACBKMT2ACCNCCDK8 | |
| SCHEMBL28723848 | 0.82 | MAPT (0.54) | MAPTACACBKMT2ACCNCCDK8 | |
| SCHEMBL27471848 | 0.79 | MAPT (0.51) | MAPTACACBKMT2ACCNCCDK8 | |
| SCHEMBL9199754 | 0.79 | ACACB (0.40) | MAPTACACBKMT2AL3MBTL1LMNA | |
| SCHEMBL6451238 | 0.78 | ALDH1A1 (0.55) | MAPTKMT2ACA2MEN1POLB | |
| SCHEMBL5132689 | 0.78 | MAPT (0.48) | MAPTACACBKMT2AMEN1L3MBTL1 | |
| SCHEMBL9197151 | 0.77 | LMNA (0.41) | MAPTACACBKMT2ACCNCCDK8 | |
| SCHEMBL10717364 | 0.77 | KDM4E (0.54) | MAPTACACBKMT2AMEN1CYP1A2 | |
| SCHEMBL3822379 | 0.77 | NQO1 (0.56) | MAPTKMT2AMEN1TDP1 | |
| SCHEMBL29658840 | 0.77 | NQO1 (0.56) | MAPTKMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046451-A2 | Diaryl-imidazole compounds, methods for their preparation, pharmaceutical drugs containing them and their use | CIBA-GEIGY AG (CH) | 1982-02-24 | — | — | EP | disclosed |