Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 12/20 | 0.40 |
| ▸ | ACACA | Q13085 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9199674 | 0.86 | ACACB (0.39) | L3MBTL1ACACBACACAKMT2AMEN1 | |
| SCHEMBL9199601 | 0.86 | ACACB (0.39) | L3MBTL1ACACBACACAALDH1A1MAPT | |
| SCHEMBL19664385 | 0.84 | KMT2A (0.43) | L3MBTL1ACACBACACAKMT2AMEN1 | |
| SCHEMBL9196824 | 0.80 | L3MBTL1 (0.38) | LMNAL3MBTL1TSHRACACBKMT2A | |
| SCHEMBL12150066 | 0.78 | CCNC (0.53) | LMNAKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL11277376 | 0.77 | MAPT (0.53) | LMNAL3MBTL1ACACBKMT2AMEN1 | |
| SCHEMBL14342283 | 0.77 | L3MBTL1 (0.50) | LMNAL3MBTL1TSHRKMT2AMEN1 | |
| SCHEMBL8096967 | 0.76 | ACACB (0.42) | LMNAACACBACACAKMT2AMEN1 | |
| SCHEMBL9199754 | 0.75 | ACACB (0.40) | LMNAL3MBTL1TSHRACACBACACA | |
| SCHEMBL5132689 | 0.74 | MAPT (0.48) | LMNAL3MBTL1TSHRACACBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278452-B1 | 2,4- and 2,5-Pyridine-dicarboxylic-acid derivatives, process for their preparation, their use and medicines based on these compounds | HOECHST AG (DE) | 1995-05-24 | — | — | EP | disclosed |
| EP-0278452-A2 | 2,4- and 2,5-Pyridine-dicarboxylic-acid derivatives, process for their preparation, their use and medicines based on these compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-17 | — | — | EP | disclosed |