Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | OXTR | P30559 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3421771 | 0.80 | AVPR1A (0.67) | AVPR1AKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL27397737 | 0.77 | VCP (0.40) | KMT2AMEN1ALDH1A1TSHRP2RX7 | |
| SCHEMBL11274510 | 0.75 | HCAR1 (0.44) | KMT2AMEN1KDM4EALDH1A1MAPK1 | |
| SCHEMBL10189850 | 0.74 | AVPR1A (0.51) | AVPR1AKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL27417384 | 0.73 | KDM4C (0.38) | AVPR1AKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL4886001 | 0.72 | ALDH1A1 (0.56) | AVPR1AKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL10189840 | 0.71 | AVPR1A (0.56) | AVPR1AKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL19068734 | 0.71 | AVPR1A (0.56) | AVPR1AKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL9299272 | 0.71 | AVPR1A (0.56) | AVPR1AKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL1562739 | 0.71 | AVPR1A (0.56) | AVPR1AKMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1092769-A | Cyclic urea derivatives, the method that contains the pharmaceutical composition of these compounds and prepare them | THOMAE GMBH DR K (DE) | 1994-09-28 | — | — | CN | claimed |
| CN-1092769-A | Cyclic urea derivatives, the method that contains the pharmaceutical composition of these compounds and prepare them | THOMAE GMBH DR K (DE) | 1994-09-28 | — | — | CN | disclosed |
| US-4338453-A | Aminoalkyl-1,2,4-triazoles | THE UPJOHN COMPANY (US) | 1982-07-06 | — | — | US | disclosed |