Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.72 |
| ▸ | ABL1 | P00519 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | FABP6 | P51161 | 1/20 | 0.66 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4345082 | 0.89 | NPSR1 (0.56) | NPSR1ABL1ALDH1A1POLBHPGD | |
| SCHEMBL4065084 | 0.87 | ABL1 (0.64) | NPSR1ABL1ALDH1A1POLBHPGD | |
| SCHEMBL13544348 | 0.85 | NPSR1 (0.97) | NPSR1ALDH1A1SMN1; SMN2CHEK2TDP1 | |
| SCHEMBL14642947 | 0.79 | ABL1 (0.69) | NPSR1ABL1ALDH1A1POLBHPGD | |
| SCHEMBL16134552 | 0.79 | ABL1 (0.69) | ABL1ALDH1A1POLBHPGDRAB9A | |
| SCHEMBL3499235 | 0.79 | ABL1 (1.00) | ABL1ALDH1A1POLBHPGDRAB9A | |
| SCHEMBL29575638 | 0.79 | ABL1 (1.00) | ABL1ALDH1A1POLBHPGDRAB9A | |
| SCHEMBL12909208 | 0.79 | ALDH1A1 (1.00) | ABL1ALDH1A1POLBHPGDRAB9A | |
| SCHEMBL2243148 | 0.78 | CHEK2 (0.80) | NPSR1ABL1ALDH1A1POLBHPGD | |
| SCHEMBL9665296 | 0.78 | RAB9A (0.62) | ABL1ALDH1A1POLBHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344957-A | Benz-acyl-benzimidazole derivatives and antiallergic compositions | CIBA-GEIGY CORPORATION (US) | 1982-08-17 | — | — | US | disclosed |
| US-4213993-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1980-07-22 | — | — | US | disclosed |
| US-4141982-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | disclosed |