SCHEMBL1127768

SCHEMBL1127768

O=C(c1ccccc1)c1cccc2c1[CH]c1ccccc1O2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 2/20 0.46
GAA P10253 2/20 0.43
MAPT P10636 1/20 0.43
ALOX5 P09917 1/20 0.42
ALDH1A1 P00352 2/20 0.41
ATM Q13315 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
P2RX4 Q99571 1/20 0.39
CYP2C9 P11712 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CDC25B P30305 1/20 0.38
TRPA1 O75762 1/20 0.38
POLB P06746 2/20 0.37
MEN1 O00255 1/20 0.37
CASP6 P55212 1/20 0.37
KMT2A Q03164 1/20 0.37
HSP90AA1 P07900 1/20 0.37
PKM P14618 1/20 0.37
CCR6 P51684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1128335 0.80 ALOX5 (0.41) ALOX5P2RX4CYP2C9TRPA1POLB
SCHEMBL27909830 0.74 AKR1C3 (0.53) AKR1C3GAAMAPTALDH1A1ATM
SCHEMBL10786669 0.72 ALOX5 (0.75) AKR1C3GAAMAPTALOX5ALDH1A1
SCHEMBL10522326 0.71 AKR1C3 (0.50) AKR1C3GAAMAPTALDH1A1ATM
SCHEMBL700595 0.70 AKR1C3 (0.85) AKR1C3GAAMAPTALDH1A1ATM
SCHEMBL29447165 0.70 AKR1C3 (0.85) AKR1C3GAAMAPTALDH1A1ATM
SCHEMBL1127529 0.70 TRPA1 (0.39) MAPTALOX5ALDH1A1ATMTDP1
SCHEMBL17850959 0.69 ATM (0.61) AKR1C3GAAMAPTALDH1A1ATM
SCHEMBL857849 0.68 AKR1C3 (0.67) AKR1C3GAAMAPTALDH1A1ATM
SCHEMBL28883310 0.68 AKR1C3 (0.81) AKR1C3GAAMAPTALDH1A1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240045330-A1 NEGATIVE PHOTOSENSITIVE COMPOSITION AND PATTERN FORMATION METHOD TOKYO OHKA KOGYO CO., LTD. (JP) 2024-02-08 US disclosed
CN-117420731-A Negative photosensitive composition and pattern forming method 东京应化工业株式会社 2024-01-19 CN disclosed
CN-113286781-B Sulfonium salt, photoacid generator, curable composition, and resist composition 三亚普罗股份有限公司 2023-08-08 CN disclosed
US-20230236505-A1 NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMATION METHOD, AND LAMINATED FILM SAN-APRO LTD. (JP) 2023-07-27 US disclosed
CN-116018558-A Negative photosensitive resin composition, pattern forming method and laminated film 三亚普罗股份有限公司 2023-04-25 CN disclosed
EP-3909943-A1 SULFONIUM SALT, PHOTOACID GENERATOR, CURABLE COMPOSITION AND RESIST COMPOSITION San-Apro Ltd. (JP) 2021-11-17 EP disclosed
WO-2020145043-A1 SULFONIUM SALT, PHOTOACID GENERATOR, CURABLE COMPOSITION AND RESIST COMPOSITION サンアプロ株式会社 2020-07-16 WO disclosed
EP-2284165-B1 SULFONIUM SALT, PHOTOACID GENERATOR, PHOTO-CURABLE COMPOSITION, AND CURED PRODUCT OF THE PHOTO-CURABLE COMPOSITION SAN APRO LTD (JP) 2013-02-20 EP disclosed
US-8278030-B2 Sulfonium salt, photoacid generator, and photocurable composition and cured body thereof SAN-APRO LIMITED (JP) 2012-10-02 US disclosed
US-20110039205-A1 SULFONIUM SALT, PHOTOACID GENERATOR, AND PHOTOCURABLE COMPOSITION AND CURED BODY THEREOF SAN-APRO LIMITED (JP) 2011-02-17 US disclosed
EP-2284165-A1 PHOSPHONIUM SALT, PHOTOACID GENERATOR, PHOTO-CURABLE COMPOSITION, AND CURED PRODUCT OF THE PHOTO-CURABLE COMPOSITION San-Apro Limited (JP) 2011-02-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110039205-A1 SULFONIUM SALT, PHOTOACID GENERATOR, AND PHOTOCURABLE COMPOSITION AND CURED BODY THEREOF ARSA, ASIC1, TST AKR1C3 983/4885GAA 2014/4885MAPT 3867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.