Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.31 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.31 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11264145 | 0.92 | KIF11 (0.37) | SIGMAR1NISCHHTR1DHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL11267326 | 0.91 | KIF11 (0.37) | SIGMAR1NISCHHTR1DHTR2CKIF11 | |
| SCHEMBL11275856 | 0.86 | KIF11 (0.35) | NISCHKIF11 | |
| Hydrochloric Acid SCHEMBL11264015 | 0.85 | KIF11 (0.34) | KIF11 | |
| SCHEMBL11275332 | 0.76 | MAPT (0.36) | HTR2CKIF11CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11263563 | 0.75 | HTR2C (0.39) | HTR2ASLC6A2HTR2CSLC6A4CYP1A2 | |
| Hydrochloric Acid SCHEMBL11273176 | 0.75 | MAPT (0.35) | HTR2CKIF11CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11260229 | 0.75 | HTR2A (0.39) | HTR2AHTR2C | |
| SCHEMBL11262097 | 0.75 | HTR2C (0.39) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL10931740 | 0.74 | PARP1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328238-A | ANTIDEPRESSANTS, ANTISECRETORY, AND ANTIULCER AGENTS | SANKYO COMPANY LIMITED (JP) | 1982-05-04 | — | — | US | disclosed |