Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28655049 | 0.76 | TDP1 (0.53) | CHRNB2CHRNA5CHRNA7CHRNA4KMT2A | |
| SCHEMBL7811263 | 0.75 | CHRNB2 (0.46) | CHRNB2CHRNA5CHRNA7CHRNA4KMT2A | |
| SCHEMBL25445958 | 0.74 | CARM1 (0.58) | CHRNB2CHRNA5CHRNA7CHRNA4KMT2A | |
| SCHEMBL22005207 | 0.74 | CARM1 (0.58) | CHRNB2CHRNA5CHRNA7CHRNA4KMT2A | |
| SCHEMBL28413234 | 0.74 | USP2 (0.35) | CHRNB2CHRNA4TDP1LMNAALDH1A1 | |
| SCHEMBL532785 | 0.74 | CARM1 (0.61) | CHRNB2CHRNA5CHRNA7CHRNA4KMT2A | |
| SCHEMBL8447322 | 0.74 | CARM1 (0.61) | CHRNB2CHRNA5CHRNA7CHRNA4KMT2A | |
| SCHEMBL11580874 | 0.74 | CHRNA7 (0.45) | CHRNA7KMT2AMEN1ATMGAA | |
| SCHEMBL7452740 | 0.73 | CARM1 (0.57) | CHRNB2CHRNA5CHRNA7CHRNA4KMT2A | |
| SCHEMBL9005573 | 0.73 | CARM1 (0.57) | CHRNB2CHRNA5CHRNA7CHRNA4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11123723-B2 | Oxidative dehydroxymethylation of alcohols to produce olefins | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-09-21 | — | — | US | disclosed |
| US-11072569-B2 | Normal alpha olefin synthesis using dehydroformylation or dehydroxymethylation | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2021-07-27 | — | — | US | disclosed |
| US-20200331823-A1 | Normal Alpha Olefin Synthesis Using Dehydroformylation or Dehydroxymethylation | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2020-10-22 | — | — | US | disclosed |
| US-10723672-B2 | Normal alpha olefin synthesis using dehydroformylation or dehydroxymethylation | CHERVON PHILLIPS CHEMICAL COMPANY LP (US) | 2020-07-28 | — | — | US | disclosed |
| US-20190262819-A1 | Oxidative Dehydroxymethylation of Alcohols to Produce Olefins | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2019-08-29 | — | — | US | disclosed |
| WO-2019165350-A1 | NORMAL ALPHA OLEFIN SYNTHESIS USING DEHYDROFORMYLATION OR DEHYDROXYMETHYLATION | BISCHOF STEVEN M (US) | 2019-08-29 | — | — | WO | disclosed |
| US-20190263729-A1 | Normal Alpha Olefin Synthesis Using Dehydroformylation or Dehydroxymethylation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190262819-A1 | Oxidative Dehydroxymethylation of Alcohols to Produce Olefins | ADH1A, ADH5, ADH1C | CHRNB2 2727/4885CHRNA5 3643/4885CHRNA7 3351/4885 |
| US-20200331823-A1 | Normal Alpha Olefin Synthesis Using Dehydroformylation or Dehydroxymethylation | ADH1A, ADH1C, DHPS | CHRNB2 2100/4885CHRNA5 2167/4885CHRNA7 1910/4885 |
| US-11123723-B2 | Oxidative dehydroxymethylation of alcohols to produce olefins | ADH1A, ADH5, ADH1C | CHRNB2 2727/4885CHRNA5 3643/4885CHRNA7 3351/4885 |
| US-10723672-B2 | Normal alpha olefin synthesis using dehydroformylation or dehydroxymethylation | ADH1A, ADH1C, DHPS | CHRNB2 2100/4885CHRNA5 2167/4885CHRNA7 1910/4885 |
| US-20190263729-A1 | Normal Alpha Olefin Synthesis Using Dehydroformylation or Dehydroxymethylation | ADH1A, ADH1C, DHPS | CHRNB2 2100/4885CHRNA5 2167/4885CHRNA7 1910/4885 |
| US-11072569-B2 | Normal alpha olefin synthesis using dehydroformylation or dehydroxymethylation | ADH1A, ADH1C, DHPS | CHRNB2 2100/4885CHRNA5 2167/4885CHRNA7 1910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.