Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 4/20 | 0.34 |
| ▸ | PPARA | Q07869 | 4/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17599298 | 0.77 | LMNA (0.41) | LMNAMEN1ALDH1A1KMT2ALTA4H | |
| SCHEMBL5245164 | 0.77 | LMNA (0.41) | LMNAMEN1ALDH1A1KMT2ALTA4H | |
| SCHEMBL7671028 | 0.73 | LMNA (0.48) | LMNAMEN1ALDH1A1KMT2ALTA4H | |
| SCHEMBL28663493 | 0.73 | LMNA (0.39) | LMNAMEN1ALDH1A1KMT2ALTA4H | |
| SCHEMBL3790591 | 0.73 | LMNA (0.48) | LMNAMEN1ALDH1A1KMT2ALTA4H | |
| SCHEMBL11883119 | 0.72 | PARP10 (0.35) | LTA4HPPARGPPARACYP1A2GAA | |
| SCHEMBL31172649 | 0.72 | LMNA (0.41) | LMNAMEN1ALDH1A1KMT2ALTA4H | |
| SCHEMBL11210416 | 0.71 | LMNA (0.47) | LMNAMEN1ALDH1A1KMT2AMTNR1A | |
| SCHEMBL15358854 | 0.71 | LTA4H (0.45) | MEN1ALDH1A1KMT2ALTA4HTSHR | |
| SCHEMBL632465 | 0.71 | LTA4H (0.45) | LMNAMEN1ALDH1A1KMT2ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4333952-A | Growth promotors for ruminants | BEECHAM GROUP LIMITED (GB) | 1982-06-08 | — | — | US | disclosed |
| EP-0022321-A1 | Benzene derivatives, their preparation and use in pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1981-01-14 | — | — | EP | disclosed |