SCHEMBL17599298

SCHEMBL17599298

OC(O)C(O)Oc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
LTA4H P09960 2/20 0.41
TSHR P16473 2/20 0.41
CA5A P35218 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
CA4 P22748 1/20 0.38
CYP2D6 P10635 2/20 0.37
MTNR1A P48039 1/20 0.37
MTNR1B P49286 1/20 0.37
ADRB2 P07550 1/20 0.37
ADRB1 P08588 1/20 0.37
ADRB3 P13945 1/20 0.37
NR1H2 P55055 1/20 0.37
BAX Q07812 1/20 0.37
CYP1A2 P05177 1/20 0.36
GAA P10253 1/20 0.36
CYP2C9 P11712 1/20 0.36
PKM P14618 1/20 0.36
CYP2C19 P33261 1/20 0.36
CHRNB4 P30926 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28663493 0.80 LMNA (0.39) LMNALTA4HTSHRCA5ACA5B
SCHEMBL3790591 0.80 LMNA (0.48) LMNALTA4HTSHRCA4CYP2D6
SCHEMBL7671028 0.80 LMNA (0.48) LMNALTA4HTSHRCA4CYP2D6
SCHEMBL11210416 0.78 LMNA (0.47) LMNACA4CYP2D6MTNR1AMTNR1B
SCHEMBL598536 0.78 LTA4H (0.45) LMNALTA4HTSHRCA5ACA5B
SCHEMBL10596047 0.78 LTA4H (0.45) LMNALTA4HTSHRCA5ACA5B
SCHEMBL11278402 0.77 LMNA (0.36) LMNALTA4HTSHRCA5ACA5B
SCHEMBL3887219 0.77 LMNA (0.41) LMNALTA4HTSHRCA4MTNR1A
SCHEMBL25325632 0.75 LMNA (0.48) LMNALTA4HTSHRCA4CYP2D6
SCHEMBL28583037 0.75 TRPA1 (0.46) LMNALTA4HTSHRCYP2D6MTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10066054-B2 Continuous method for manufacturing a polyester from cyclic ester monomer SULZER CHEMTECH AG (CH) 2018-09-04 US disclosed
US-20170240697-A1 A Continuous Method for Manufacturing a Polyester from Cyclic Ester Monomer SULZER CHEMTECH AG (CH) 2017-08-24 US disclosed
EP-2998337-A1 A method for stabilizing a condensed phase composition including a cyclic ester for example in a process of manufacturing a polyester Sulzer Chemtech AG (CH) 2016-03-23 EP disclosed