Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26620963 | 0.85 | CYP1A2 (0.52) | ALDH1A1PPARGPPARAMAOACYP1A2 | |
| SCHEMBL15358854 | 0.82 | LTA4H (0.45) | LTA4HTSHRCA4KCNA3MEN1 | |
| SCHEMBL9319424 | 0.82 | LTA4H (0.45) | LTA4HTSHRCA4KCNA3MEN1 | |
| SCHEMBL1981551 | 0.78 | TSHR (0.41) | LTA4HTSHRCA4KCNA3MEN1 | |
| SCHEMBL11072413 | 0.78 | TSHR (0.41) | LTA4HTSHRCA4KCNA3MEN1 | |
| SCHEMBL2001545 | 0.78 | CA4 (0.43) | LTA4HTSHRCA4MEN1ALDH1A1 | |
| SCHEMBL5245164 | 0.78 | LMNA (0.41) | LTA4HTSHRCA4MEN1ALDH1A1 | |
| SCHEMBL7938258 | 0.78 | TSHR (0.41) | LTA4HTSHRCA4KCNA3MEN1 | |
| SCHEMBL10758577 | 0.78 | TSHR (0.41) | LTA4HTSHRCA4KCNA3MEN1 | |
| SCHEMBL4267169 | 0.78 | TSHR (0.41) | LTA4HTSHRCA4KCNA3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116231090-B | High-pressure-resistant flame-retardant electrolyte compatible with graphite and lithium ion battery | 华中科技大学 | 2023-08-11 | — | — | CN | claimed |
| CN-116231090-A | High-pressure-resistant flame-retardant electrolyte compatible with graphite and lithium ion battery | 华中科技大学 | 2023-06-06 | — | — | CN | claimed |
| CN-114539036-A | Method for efficiently synthesizing trichloromethoxybenzene by controlling chlorination depth | 金凯(辽宁)生命科技股份有限公司 | 2022-05-27 | — | — | CN | claimed |
| EP-2258354-B1 | Compounds and methods for controlling alcohol intake | JNC INNOVATIONS (FR) | 2013-05-08 | — | — | EP | claimed |
| EP-2258354-A1 | Compounds and methods for controlling alcohol intake | JNC Innovations (FR) | 2010-12-08 | — | — | EP | claimed |
| US-7652057-B2 | Pyrazolones as 11b-HSD1 inhibitors for diabetes | HOFFMAN-LA ROCHE INC. (US) | 2010-01-26 | — | — | US | claimed |
| EP-1924562-A2 | PYRAZOLONE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2008-05-28 | — | — | EP | claimed |
| EP-1786405-A2 | COMPOUNDS AND METHODS FOR CONTROLLING ALCOHOL INTAKE | Colombani, Jean-Noël (FR) | 2007-05-23 | — | — | EP | claimed |
| WO-2007025880-A2 | PYRAZOLONE DERIVATIVES AS 11-BETA HSD1 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-03-08 | — | — | WO | claimed |
| US-20070049574-A1 | New pyrazolones as 11b-HSD1 inhibitors for diabetes | F. HOFFMANN-LA ROCHE AG (CH) | 2007-03-01 | — | — | US | claimed |
| WO-2006018521-A2 | COMPOUNDS AND METHODS FOR CONTROLLING ALCOHOL INTAKE | COLOMBANI JEAN-NOEL (FR) | 2006-02-23 | — | — | WO | claimed |
| WO-1994001394-A1 | PREPARATION OF N-ARYL AMIDES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1994-01-20 | — | — | WO | claimed |
| EP-3452439-B1 | PROCESS FOR PREPARATION OF 3,6-DICHLORO-2-METHOXYBENZOIC ACID (DICAMBA) | GHARDA KEKI HORMUSJI (IN) | 2025-06-11 | — | — | EP | disclosed |
| CN-119023864-A | Method for measuring olfactory substances in water by ionic liquid single-drop suspended liquid-phase microextraction gas chromatography | 陈东 | 2024-11-26 | — | — | CN | disclosed |
| WO-2024219304-A1 | SOIL CONTAMINATION EVALUATION METHOD | 清水建設株式会社 | 2024-10-24 | — | — | WO | disclosed |
| CN-118652199-A | Di-diazeniumdiolate nitric oxide donor, preparation and application | 浙江大学 | 2024-09-17 | — | — | CN | disclosed |
| US-4327027-A | Chemical detoxification of toxic chlorinated aromatic compounds | VERTAC CHEMICAL CORPORATION (US) | 1982-04-27 | — | — | US | disclosed |
| EP-0021294-A1 | Chemical detoxification of toxic chlorinated aromatic compounds | Vertac Chemical Corporation (US) | 1981-01-07 | — | — | EP | disclosed |
| US-4101323-A | Radiation-sensitive copying composition | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-07-18 | — | — | US | disclosed |
| US-3969529-A | Phenoxyacetic acid derivatives as diuretic agents | C.E.R.P.H.A. (FR) | 1976-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049574-A1 | New pyrazolones as 11b-HSD1 inhibitors for diabetes | HSD11B1, HSD17B1, HSD17B7 | LTA4H 796/4885TSHR 1762/4885CA4 1974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.