Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278426 | 1.00 | ALDH1A1 (0.40) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL1132073 | 0.81 | ALDH1A1 (0.39) | ALDH1A1LMNAALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL27976566 | 0.76 | ALDH1A1 (0.42) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL305582 | 0.74 | ALDH1A1 (0.56) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL11147178 | 0.74 | ALDH1A1 (0.56) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL305583 | 0.74 | ALDH1A1 (0.56) | ALDH1A1LMNAHSD17B10 | |
| Ammonia Solution, Strong SCHEMBL6537012 | 0.72 | ALDH1A1 (0.53) | ALDH1A1LMNAHSD17B10 | |
| Ammonia Solution, Strong SCHEMBL7633955 | 0.72 | ALDH1A1 (0.53) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL862169 | 0.71 | — | — | |
| SCHEMBL6889293 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4315939-A | Piperidine derivatives of 4,5-dialkyl-3-hydroxy-pyrrole-2-carboxylic acid esters, pharmaceutical formulations containing these compounds and use in treating cardiac arrhythmias | BASF AKTIENGESELLSCHAFT (DE) | 1982-02-16 | — | — | US | disclosed |