SCHEMBL305582

SCHEMBL305582

COC(=O)/C(C)=C(/C)C(=O)OC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
MGAM O43451 1/20 0.40
GAA P10253 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
TET2 Q6N021 1/20 0.38
EGLN1 Q9GZT9 1/20 0.38
TSHR P16473 5/20 0.37
KEAP1 Q14145 1/20 0.37
NFE2L2 Q16236 1/20 0.37
HCAR2 Q8TDS4 1/20 0.37
LMNA P02545 1/20 0.36
KDM4E B2RXH2 1/20 0.35
CA2 P00918 1/20 0.35
PTGS1 P23219 1/20 0.35
MMP12 P39900 1/20 0.35
NFKB1 P19838 1/20 0.33
HSD17B10 Q99714 1/20 0.33
THPO P40225 1/20 0.33
FFAR3 O14843 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL305583 1.00 ALDH1A1 (0.56) ALDH1A1MGAMGAASIMGAM2
SCHEMBL11147178 1.00 ALDH1A1 (0.56) ALDH1A1MGAMGAASIMGAM2
Ammonia Solution, Strong SCHEMBL7633955 0.96 ALDH1A1 (0.53) ALDH1A1MGAMGAASIMGAM2
Ammonia Solution, Strong SCHEMBL6537012 0.96 ALDH1A1 (0.53) ALDH1A1MGAMGAASIMGAM2
SCHEMBL5843201 0.87 ALDH1A1 (0.46) ALDH1A1MGAMGAASIMGAM2
SCHEMBL7771273 0.87 ALDH1A1 (0.46) ALDH1A1MGAMGAASIMGAM2
SCHEMBL5843191 0.87 ALDH1A1 (0.46) ALDH1A1MGAMGAASIMGAM2
SCHEMBL12172504 0.87 ALDH1A1 (0.46) ALDH1A1MGAMGAASIMGAM2
SCHEMBL370133 0.86
SCHEMBL2352707 0.85 ALDH1A1 (0.43) ALDH1A1MGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118108878-A Organic polymer carrier and preparation method and application thereof 中国石油天然气股份有限公司 2024-05-31 CN claimed
CN-113105850-A Waterborne polyurethane-acrylate-epoxidized soybean oil label adhesive and preparation method thereof 华南理工大学 2021-07-13 CN claimed
CN-107216845-B Siloxane-terminated polyurethane sealant and preparation method thereof 华南理工大学 2020-08-18 CN claimed
CN-108395867-A A kind of high-performance water-based antibacterial adhesive of safety and environmental protection and preparation method thereof 华南理工大学 2018-08-14 CN claimed
CN-107216845-A A kind of environment-friendly type end siloxy group polyurethane sealant and preparation method thereof 华南理工大学 2017-09-29 CN claimed
CN-104558422-B Method for preparing thermoplastic cellulose based copolymer 天津工业大学 2017-02-22 CN claimed
CN-104558422-A Method for preparing thermoplastic cellulose based copolymer and application of thermoplastic cellulose based copolymer UNIV TIANJIN POLYTECHNIC 2015-04-29 CN claimed
CN-118108878-A Organic polymer carrier and preparation method and application thereof 中国石油天然气股份有限公司 2024-05-31 CN disclosed
CN-107216845-B Siloxane-terminated polyurethane sealant and preparation method thereof 华南理工大学 2020-08-18 CN disclosed
US-20180277881-A1 SECONDARY BATTERY, BATTERY PACK, ELECTRIC VEHICLE, POWER STORAGE SYSTEM, ELECTRIC TOOL, ELECTRONIC DEVICE MURATA MANUFACTURING CO., LTD. (JP) 2018-09-27 US disclosed
CN-108475818-A Secondary battery, battery pack, electric vehicle, electric power storage system, electric power tool, and electronic device 株式会社村田制作所 2018-08-31 CN disclosed
CN-108395867-A A kind of high-performance water-based antibacterial adhesive of safety and environmental protection and preparation method thereof 华南理工大学 2018-08-14 CN disclosed
CN-107531610-A Process for recovering dialkyl succinate or maleate 庄信万丰戴维科技有限公司 2018-01-02 CN disclosed
US-20120071457-A1 METALLO-BETA-LACTAMASE INHIBITORS CHIKAUCHI KEN (JP) 2012-03-22 US disclosed
US-8093294-B2 Bacterial infections; effective for recovering the activities of beta-lactam antibiotics; 2-ethyl-3-methylmaleic acid dimethyl ester; maleic acid derivatives and/or dihydrofuranyl derivatives MEIJI SEIKA KAISHA, LTD. (JP) 2012-01-10 US disclosed
CN-101267815-A metallo-beta-lactamase inhibitors MEIJI SEIKA KAISHA (JP) 2008-09-17 CN disclosed
EP-1941873-A1 METALLO-BETA-LACTAMASE INHIBITOR MEIJI SEIKA KAISHA LTD. (JP) 2008-07-09 EP disclosed
US-20080090825-A1 Metallo-beta-lactamase inhibitors MEIJI SEIKA KAISHA, LTD. (JP) 2008-04-17 US disclosed
US-4404301-A Polymeric light stabilizers having at least one 2,2,6,6-tetraalkyl piperidyl group and synthetic resin compositions containing the same ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1983-09-13 US disclosed
US-4383053-A Antifouling paints having fumaric acid ester polymer NIPPON OIL AND FATS CO., LTD. (JP) 1983-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080090825-A1 Metallo-beta-lactamase inhibitors ME1, MGAM, GAA ALDH1A1 372/4885MGAM 2/4885GAA 3/4885
US-20120071457-A1 METALLO-BETA-LACTAMASE INHIBITORS ME1, MGAM, GAA ALDH1A1 372/4885MGAM 2/4885GAA 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.