Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11190155 | 0.85 | SMN1; SMN2 (0.49) | ALDH1A1TSHRSMN1; SMN2POLBHTT | |
| SCHEMBL9453242 | 0.84 | POLB (0.54) | ALDH1A1TSHRSMN1; SMN2POLBHTT | |
| SCHEMBL10770854 | 0.80 | RAB9A (0.55) | ALDH1A1SMN1; SMN2POLBHTTMEN1 | |
| SCHEMBL22103682 | 0.79 | ALDH1A1 (0.66) | ALDH1A1TSHRSMN1; SMN2POLBMAPK1 | |
| SCHEMBL11260224 | 0.76 | CYP1A2 (0.49) | ALDH1A1SMN1; SMN2HTTMAPK1MEN1 | |
| SCHEMBL30136232 | 0.75 | POLB (0.58) | ALDH1A1TSHRSMN1; SMN2POLBHTT | |
| SCHEMBL1395802 | 0.75 | POLB (0.58) | ALDH1A1TSHRSMN1; SMN2POLBHTT | |
| SCHEMBL14817539 | 0.75 | POLB (0.66) | ALDH1A1SMN1; SMN2POLBMAPK1MEN1 | |
| SCHEMBL11278636 | 0.75 | ABCC1 (0.60) | POLBMEN1KMT2AKDM4E | |
| SCHEMBL9474101 | 0.74 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350700-A | ANALGESIC, ANTIINFLAMMATORY, ANTIPYRETIC | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1982-09-21 | — | — | US | disclosed |
| US-4287207-A | USED AS AN ANALGESIC, ANTIPYRETIC OR ANTIINFLAMMATORY AGENT | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1981-09-01 | — | — | US | disclosed |