Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | AGER | Q15109 | 1/20 | 0.38 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9300779 | 0.76 | PDE10A (0.52) | PDE10AKDM4EMEN1KMT2AMAPT | |
| SCHEMBL11067371 | 0.74 | MEN1 (0.38) | PDE10AKDM4EMEN1KMT2AMAPT | |
| SCHEMBL11069700 | 0.72 | HTR7 (0.57) | KDM4EMAPTTDP1GAA | |
| SCHEMBL17656090 | 0.68 | ALOX5 (0.40) | PDE10AKDM4EMEN1KMT2AMAPT | |
| SCHEMBL6730776 | 0.67 | MEN1 (0.42) | PDE10AKDM4EMEN1KMT2AMAPT | |
| SCHEMBL3141201 | 0.67 | TLR8 (0.45) | PDE10AKDM4ETSHRTDP1L3MBTL1 | |
| SCHEMBL29342321 | 0.67 | CYP19A1 (0.43) | KDM4EMEN1KMT2ATNFTLR7 | |
| SCHEMBL13852949 | 0.66 | KDM4E (0.50) | PDE10AKDM4EMAPTTSHRCYP3A4 | |
| SCHEMBL16512991 | 0.66 | TLR8 (0.64) | TLR7CYP1A2 | |
| SCHEMBL822550 | 0.66 | DHODH (0.51) | PDE10AKDM4EMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360674-A | Naphth[1,2-d]imidazoles | GRUPPO LEPETIT S.P.A. (IT) | 1982-11-23 | — | — | US | disclosed |