SCHEMBL1127908

SCHEMBL1127908

CCOc1cc2ccccc2c2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 1/20 0.50
GPR84 Q9NQS5 1/20 0.47
ADORA1 P30542 2/20 0.45
ALOX5 P09917 1/20 0.45
ADORA2A P29274 1/20 0.45
ALDH1A1 P00352 3/20 0.44
LMNA P02545 3/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
SLC2A1 P11166 1/20 0.42
TRPM4 Q8TD43 1/20 0.42
HIF1A Q16665 1/20 0.41
CYP1B1 Q16678 1/20 0.41
HSD17B10 Q99714 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
S1PR1 P21453 1/20 0.40
S1PR3 Q99500 1/20 0.40
PDE10A Q9Y233 1/20 0.40
MAPT P10636 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10484241 0.87 HPRT1 (0.50) TLR8ADORA1ALOX5ADORA2AALDH1A1
SCHEMBL28267274 0.85 TLR8 (0.53) TLR8GPR84L3MBTL1MEN1TSHR
SCHEMBL14288499 0.84 NCF1 (0.58) TLR8GPR84ALDH1A1L3MBTL1NPC1
SCHEMBL3819123 0.81 TLR8 (0.44) TLR8ADORA1ALOX5ADORA2AALDH1A1
SCHEMBL8560575 0.81 TLR8 (0.47) TLR8ALOX5ALDH1A1LMNAL3MBTL1
SCHEMBL13311250 0.81 CYP1A2 (0.52) TLR8ADORA1ALOX5ADORA2AALDH1A1
SCHEMBL21122175 0.81 HPRT1 (0.52) ALOX5ALDH1A1TSHR
SCHEMBL9872788 0.81 HPRT1 (0.52) ALOX5ALDH1A1TSHR
SCHEMBL3818602 0.81 TLR8 (0.58) TLR8ALOX5ALDH1A1LMNAL3MBTL1
SCHEMBL29631653 0.80 ALOX5 (0.47) TLR8ALOX5ALDH1A1LMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12624392-B2 Molecular array generation using photoresist 10X GENOMICS, INC. (US) 2026-05-12 US disclosed
EP-4516394-A2 HIGH DEFINITION MOLECULAR ARRAY FEATURE GENERATION USING PHOTORESIST 10x Genomics, Inc. (US) 2025-03-05 EP disclosed
EP-4481059-A2 MOLECULAR ARRAY GENERATION USING PHOTORESIST 10x Genomics, Inc. (US) 2024-12-25 EP disclosed
EP-4405094-B1 HIGH DEFINITION MOLECULAR ARRAY FEATURE GENERATION USING PHOTORESIST 10X GENOMICS INC (US) 2024-12-18 EP disclosed
EP-4271511-B1 MOLECULAR ARRAY GENERATION USING PHOTORESIST 10X GENOMICS INC (US) 2024-10-09 EP disclosed
EP-4405094-A1 HIGH DEFINITION MOLECULAR ARRAY FEATURE GENERATION USING PHOTORESIST 10X Genomics, Inc. (US) 2024-07-31 EP disclosed
US-20240167077-A1 COVALENT ATTACHMENT OF SPLINT OLIGONUCLEOTIDES FOR MOLECULAR ARRAY GENERATION USING LIGATION 10X GENOMICS, INC. (US) 2024-05-23 US disclosed
US-20240076656-A1 HIGH DEFINITION MOLECULAR ARRAY FEATURE GENERATION USING PHOTORESIST 10X GENOMICS, INC. (US) 2024-03-07 US disclosed
US-20240060127-A1 METHODS AND SYSTEMS FOR LIGHT-CONTROLLED SURFACE PATTERNING USING PHOTOMASKS 10X GENOMICS, INC. 2024-02-22 US disclosed
WO-2024006827-A1 METHODS AND SYSTEMS FOR LIGHT-CONTROLLED SURFACE PATTERNING USING PHOTOMASKS 10X GENOMICS, INC. (US) 2024-01-04 WO disclosed
EP-1752463-A1 NOVEL FLUORINATED ALKYLFLUOROPHOSPHORIC ACID SALT OF ONIUM AND TRANSITION METAL COMPLEX San-Apro Limited (JP) 2007-02-14 EP disclosed
EP-1201638-B1 PHOTOCURABLE COMPOSITION CONTAINING IODONIUM SALT COMPOUND NIPPON SODA CO (JP) 2004-06-23 EP disclosed
US-6677390-B1 CURABLE MIXTURES COMPRISING SENSITIZERS AND HALOGEN COMPOUNDS SUCH AS 4-CARBOXYMETHOXYPHENYL-2',4',6'-TRIMETHYLPHENYL-IODONIUM HEXAFLUOROPHOSPHATE, USED AS NONTOXIC ACID GENERATORS OR CATALYSTS; QUICK SETTING NIPPON SODA CO., LTD. (JP) 2004-01-13 US disclosed
US-6558871-B1 Photopolymerization initiator comprising at least one of diaryliodonium salt NIPPON SODA CO. LTD. (JP) 2003-05-06 US disclosed
EP-1201638-A1 PHOTOCURABLE COMPOSITION CONTAINING IODONIUM SALT COMPOUND NIPPON SODA CO., LTD. (JP) 2002-05-02 EP disclosed
EP-1106639-A1 PHOTOCURABLE COMPOSITION CONTAINING IODONIUM SALT COMPOUND NIPPON SODA CO., LTD. (JP) 2001-06-13 EP disclosed
US-4808625-A ANTITUMOR AGENTS BURROUGHS WELLCOME CO. (US) 1989-02-28 US disclosed
EP-0125701-B1 POLYCYCLIC AROMATIC COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1988-08-03 EP disclosed
US-4719055-A ANTITUMOR BURROUGHS WELLCOME CO. (US) 1988-01-12 US disclosed
EP-0125701-A2 Polycyclic aromatic compounds THE WELLCOME FOUNDATION LIMITED (GB) 1984-11-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624392-B2 Molecular array generation using photoresist POLL, LIG4, LIG3 TLR8 1361/4885GPR84 3405/4885ADORA1 2371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.