Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11285336 | 0.82 | ALDH1A1 (0.44) | ALDH1A1GAAKDM4EMAPTLMNA | |
| SCHEMBL11285782 | 0.82 | NOTUM (0.49) | ALDH1A1GAAKDM4EMAPTLMNA | |
| SCHEMBL11274930 | 0.78 | IP6K1 (0.51) | MMP2ALDH1A1GAAKDM4EHPGD | |
| SCHEMBL11279016 | 0.71 | KMT2A (0.62) | ALDH1A1GAAKDM4EMAPTLMNA | |
| SCHEMBL11106926 | 0.71 | MEN1 (0.50) | ALDH1A1GAAKDM4EMAPTHPGD | |
| Biphenyl SCHEMBL8525491 | 0.68 | ALDH1A1 (0.61) | ALDH1A1GAAKDM4EMAPTLMNA | |
| SCHEMBL17060019 | 0.67 | ALDH1A1 (0.50) | ALDH1A1GAAKDM4EMAPTLMNA | |
| SCHEMBL13739142 | 0.66 | MMP2 (0.53) | MMP2ALDH1A1GAAKDM4EMAPT | |
| Anthranilic Acid SCHEMBL15167006 | 0.66 | MAPT (0.57) | MMP2ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL2505916 | 0.66 | NPC1 (0.58) | ALDH1A1GAAKDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056144-A1 | Carboxylic acid derivatives, their preparation and use as pharmaceuticals | Dr. Karl Thomae GmbH (DE) | 1982-07-21 | — | — | EP | disclosed |