Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11279174 | 0.82 | MMP2 (0.44) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL11285782 | 0.82 | NOTUM (0.49) | ALDH1A1KDM4EHPGDLMNAGAA | |
| SCHEMBL5532623 | 0.80 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL6105725 | 0.78 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL30159879 | 0.78 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL6828943 | 0.78 | KMT2A (0.56) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| Biphenyl SCHEMBL1577458 | 0.74 | NPC1 (0.57) | ALDH1A1KDM4EHPGDHSD17B10HTT | |
| SCHEMBL5745223 | 0.73 | ADRB1 (0.49) | ALDH1A1KDM4EHPGDHSD17B10MYC | |
| SCHEMBL29512757 | 0.72 | NOS2 (0.39) | ALDH1A1KDM4EGAAMAPTHTT | |
| SCHEMBL3824512 | 0.72 | KDM4E (0.46) | ALDH1A1KDM4EHPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056144-A1 | Carboxylic acid derivatives, their preparation and use as pharmaceuticals | Dr. Karl Thomae GmbH (DE) | 1982-07-21 | — | — | EP | disclosed |