Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 16/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11282374 | 0.85 | KMT2A (0.39) | ELANEALDH1A1LMNAADRB2MEN1 | |
| SCHEMBL11284109 | 0.83 | ELANE (0.53) | ELANEALDH1A1MEN1MAPTRECQL | |
| SCHEMBL11290593 | 0.83 | ALDH1A1 (0.46) | ELANEALDH1A1LMNACYP3A4HIF1A | |
| Hydrochloric Acid SCHEMBL11282567 | 0.82 | ADRB2 (0.47) | ELANEALDH1A1LMNACYP3A4HIF1A | |
| SCHEMBL11279189 | 0.81 | ALOX15 (0.42) | ELANEALDH1A1MEN1MAPTRECQL | |
| SCHEMBL11282093 | 0.81 | ELANE (0.42) | ELANEALDH1A1LMNACYP3A4HIF1A | |
| SCHEMBL11109081 | 0.79 | ELANE (0.49) | ELANEALDH1A1LMNACYP3A4HIF1A | |
| SCHEMBL11102277 | 0.79 | ELANE (0.47) | ELANEALDH1A1LMNACYP3A4HIF1A | |
| Hydrochloric Acid SCHEMBL11283476 | 0.78 | ALDH1A1 (0.36) | ALDH1A1MEN1MAPTRECQLKMT2A | |
| SCHEMBL11288055 | 0.77 | ALOX15 (0.49) | ELANEALDH1A1LMNACYP3A4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |