Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11286111 | 0.89 | ELANE (0.49) | ELANEALDH1A1MEN1KMT2ASLC2A1 | |
| Hydrochloric Acid SCHEMBL11290086 | 0.88 | NR1H4 (0.37) | ELANENR1H4PDE4BALDH1A1MEN1 | |
| SCHEMBL11282096 | 0.87 | ALDH1A1 (0.40) | ELANEPDE4BALDH1A1ADRB2 | |
| SCHEMBL11281249 | 0.83 | ALDH1A1 (0.38) | ELANEALDH1A1ADRB2ALPLALPG | |
| Hydrochloric Acid SCHEMBL11284028 | 0.82 | TSHR (0.41) | PDE4BALDH1A1MEN1KMT2AGAA | |
| SCHEMBL11291258 | 0.80 | ALOX15 (0.44) | THRATHRBSMPD1 | |
| SCHEMBL11306292 | 0.80 | KMT2A (0.51) | ALDH1A1KMT2ASLC2A1MAPTSMN1; SMN2 | |
| SCHEMBL11285998 | 0.79 | ALOX15 (0.42) | PDE4BPDE4APDE4CPDE4DADRB2 | |
| SCHEMBL11284281 | 0.79 | ESR1 (0.44) | NR1H4PDE4BALDH1A1MEN1KMT2A | |
| SCHEMBL11285631 | 0.79 | ADRB2 (0.43) | ALDH1A1MEN1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |