Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | STAT6 | P42226 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | PLK1 | P53350 | 1/20 | 0.59 |
| ▸ | CDC25B | P30305 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 4/20 | 0.48 |
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11598244 | 0.85 | HPGDS (0.69) | HPGDSCYP2C9ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4835983 | 0.85 | HPGDS (0.73) | HPGDSCYP2C9ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4097579 | 0.85 | HPGDS (0.73) | HPGDSCYP2C9ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL245751 | 0.83 | HPGDS (0.71) | HPGDSCYP2C9ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4519297 | 0.83 | HPGDS (1.00) | HPGDSCYP2C9ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL535326 | 0.81 | PLK1 (0.65) | HPGDSCYP2C9ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL24396937 | 0.81 | HPGDS (0.68) | HPGDSCYP2C9ALDH1A1CYP1A2CYP3A4 | |
| Menbutone SCHEMBL30277792 | 0.81 | CYP2C9 (0.69) | HPGDSCYP2C9ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL29936431 | 0.81 | HPGDS (0.68) | HPGDSCYP2C9ALDH1A1CYP1A2CYP3A4 | |
| Menbutone SCHEMBL1641812 | 0.81 | CYP2C9 (0.69) | HPGDSCYP2C9ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327022-A | Heterocyclic alkyl naphthols | STERLING DRUG INC. (US) | 1982-04-27 | — | — | US | disclosed |