Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | STAT6 | P42226 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | PLK1 | P53350 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | CDC25B | P30305 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 4/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4097579 | 0.85 | HPGDS (0.73) | HPGDSCYP2C9ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4835983 | 0.85 | HPGDS (0.73) | HPGDSCYP2C9ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11277750 | 0.84 | MAPT (0.54) | HPGDSCYP2C9ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11279449 | 0.83 | HPGDS (0.71) | HPGDSCYP2C9ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4519297 | 0.83 | HPGDS (1.00) | HPGDSCYP2C9ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11598244 | 0.82 | HPGDS (0.69) | HPGDSCYP2C9ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4028585 | 0.81 | PLK1 (0.65) | HPGDSCYP2C9ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL24396937 | 0.81 | HPGDS (0.68) | HPGDSCYP2C9ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL29936431 | 0.81 | HPGDS (0.68) | HPGDSCYP2C9ALDH1A1CYP1A2CYP3A4 | |
| Menbutone SCHEMBL1641812 | 0.81 | CYP2C9 (0.69) | HPGDSCYP2C9ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9644099-B2 | Violet laser excitable dyes and their method of use | Life Technologies Corporation (US) | 2017-05-09 | — | — | US | disclosed |
| US-20160355682-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2016-12-08 | — | — | US | disclosed |
| US-20150050685-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | LIFE TECHNOLOGIES CORP (US) | 2015-02-19 | — | — | US | disclosed |
| US-8822695-B2 | Violet laser excitable dyes and their method of use | Life Technologies Corporation (US) | 2014-09-02 | — | — | US | disclosed |
| US-20130273569-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | LIFE TECHNOLOGIES CORP (US) | 2013-10-17 | — | — | US | disclosed |
| US-8415477-B2 | Violet laser excitable dyes and their method of use | Life Technologies Corporation (US) | 2013-04-09 | — | — | US | disclosed |
| US-8158801-B2 | Violet laser excitable dyes and their method of use | Life Technologies Corporation (US) | 2012-04-17 | — | — | US | disclosed |
| US-20120004397-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | Life Technologies Corporation (US) | 2012-01-05 | — | — | US | disclosed |
| EP-1928822-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | INVITROGEN CORPORATION (US) | 2008-06-11 | — | — | EP | disclosed |
| US-20070077549-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | INVITROGEN CORPORATION (US) | 2007-04-05 | — | — | US | disclosed |
| WO-2007038659-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | INVITROGEN CORPORATION (US) | 2007-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130273569-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | KLK3, ALDH1A2, SPR | HPGDS 3531/4885CYP2C9 833/4885ALDH1A1 145/4885 |
| US-20070077549-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | KLK3, ALDH1A2, SPR | HPGDS 3531/4885CYP2C9 833/4885ALDH1A1 145/4885 |
| US-20120004397-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | KLK3, ALDH1A2, SPR | HPGDS 3531/4885CYP2C9 833/4885ALDH1A1 145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.