Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | STAT6 | P42226 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | PLK1 | P53350 | 1/20 | 0.61 |
| ▸ | CDC25B | P30305 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 4/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HMGCR | P04035 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4109331 | 0.90 | HPGDS (0.59) | HPGDSCYP2C9ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4835983 | 0.86 | HPGDS (0.73) | HPGDSCYP2C9ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4519297 | 0.85 | HPGDS (1.00) | HPGDSCYP2C9ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11279449 | 0.85 | HPGDS (0.71) | HPGDSCYP2C9ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL245751 | 0.85 | HPGDS (0.71) | HPGDSCYP2C9ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11598244 | 0.83 | HPGDS (0.69) | HPGDSCYP2C9ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL24396937 | 0.82 | HPGDS (0.68) | HPGDSCYP2C9ALDH1A1CYP1A2CYP3A4 | |
| Menbutone SCHEMBL30277792 | 0.82 | CYP2C9 (0.69) | HPGDSCYP2C9ALDH1A1CYP1A2CYP3A4 | |
| Menbutone SCHEMBL1641812 | 0.82 | CYP2C9 (0.69) | HPGDSCYP2C9ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL562156 | 0.82 | HPGDS (0.68) | HPGDSCYP2C9ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2678017-B1 | ASYMMETRIC UREAS AND MEDICAL USES THEREOF | HELSINN HEALTHCARE SA (CH) | 2017-04-05 | — | — | EP | disclosed |
| US-20090221645-A1 | Dihydroimidazothiazole Derivatives | PROSIDION LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |
| US-20090221645-A1 | Dihydroimidazothiazole Derivatives | PROSIDION LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |
| US-20090221645-A1 | Dihydroimidazothiazole Derivatives | PROSIDION LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |
| EP-0200942-B1 | NEW DERIVATIVES OF AN AMINOKETONE | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1993-08-25 | — | — | EP | disclosed |
| US-5103022-A | Reacting dl-2-methyl-1-(4-trifluoromethylphenyl)-3-pyrrolidino -1-propanone with l-acetylphenylglycine to form corresponding diastereomeric salt, deposition, isolation of l-2-methyl-1-(4-trifluoromethylphenyl)-3-pyrrolidino-1-propanone | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1992-04-07 | — | — | US | disclosed |
| US-3985896-A | Benzophenalenofurans | SMITHKLINE CORPORATION (US) | 1976-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221645-A1 | Dihydroimidazothiazole Derivatives | TPH1, HTR3B, HTR1A | HPGDS 2194/4885CYP2C9 293/4885ALDH1A1 195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.