SCHEMBL112795

SCHEMBL112795

CC1=C(O)C(=O)c2ccccc2C1=O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APAF1 O14727 2/20 0.68
TDP2 O95551 2/20 0.68
CDC25B P30305 6/20 0.56
CDC25A P30304 4/20 0.56
AURKA O14965 1/20 0.56
AURKB Q96GD4 1/20 0.56
S100A4 P26447 5/20 0.52
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
POLB P06746 2/20 0.48
MAP2K7 O14733 2/20 0.48
P2RX7 Q99572 2/20 0.48
MAPT P10636 2/20 0.48
MAOA P21397 2/20 0.48
BCL2 P10415 1/20 0.48
MCL1 Q07820 1/20 0.48
KDM4E B2RXH2 1/20 0.48
CES2 O00748 1/20 0.48
TERT O14746 1/20 0.48
NPC1 O15118 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29728498 1.00 APAF1 (0.68) APAF1TDP2CDC25BCDC25AAURKA
SCHEMBL31606781 0.91 APAF1 (0.68) APAF1TDP2CDC25BCDC25AAURKA
SCHEMBL10216429 0.91 APAF1 (0.61) APAF1TDP2CDC25BCDC25AAURKA
SCHEMBL29929043 0.84 APAF1 (0.58) APAF1TDP2CDC25BCDC25AAURKA
SCHEMBL29678361 0.82 APAF1 (1.00) APAF1TDP2CDC25BS100A4MEN1
SCHEMBL571026 0.82 CDC25B (0.68) APAF1TDP2CDC25BCDC25AAURKA
SCHEMBL29941466 0.82 CDC25B (0.68) APAF1TDP2CDC25BCDC25AAURKA
SCHEMBL461648 0.82 APAF1 (1.00) APAF1TDP2CDC25BS100A4MEN1
Water SCHEMBL8664586 0.79 CDC25B (0.65) APAF1TDP2CDC25BCDC25AAURKA
SCHEMBL23271984 0.79 MAOA (0.73) APAF1TDP2MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 722 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 US claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
WO-2022182523-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
WO-2021158573-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 WO claimed
WO-2021158575-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 WO claimed
US-7799092-B2 Composition for simultaneously bleaching and dyeing keratin fibers, comprising at least one anionic or nonionic direct dye and at least one associative polymer L'OREAL S.A. (FR) 2010-09-21 US claimed
US-7736395-B2 direct dyes L'OREAL S.A. (FR) 2010-06-15 US claimed
EP-1738801-B1 Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an inert organic liquid OREAL (FR) 2010-06-09 EP claimed
EP-1738800-B1 Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an asociative polymer OREAL (FR) 2010-06-09 EP claimed
EP-1261254-A2 METHOD OF CONTROLLING ZOOLOGICAL AND AQUATIC PLANT GROWTH Garnett, Inc. (US) 2002-12-04 EP claimed
US-6458168-B1 Hair dyeing method using an aliphatic cationic amine and compound chosen from an aldehyde, a ketone, a quinone, a di-imino-isoindoline, and a 3-aminoisoindolone derivative L'OREAL S.A. (FR) 2002-10-01 US claimed
US-6451067-B1 HAIR DYE MIXTURE L'OREAL S.A. (FR) 2002-09-17 US claimed
WO-2001060971-A2 METHOD OF CONTROLLING ZOOLOGICAL AND AQUATIC PLANT GROWTH GARNETT, INC. (US) 2001-08-23 WO claimed
EP-0498707-B1 Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent OREAL (FR) 1995-08-02 EP claimed
US-5411675-A Mixtures of aromatic diamines, hydroxynaphthoquinone, acid and silica sol as antiscaling agents SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-05-02 US claimed
EP-0498707-A1 Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent L'OREAL (FR) 1992-08-12 EP claimed
US-5064442-A HAIR DYES L'OREAL (FR) 1991-11-12 US claimed
US-4888026-A HAIR DYES; OXIDATION RESISTANCE L'OREAL (FR) 1989-12-19 US claimed
EP-0152852-A2 Antimicrobial agent for treating buildings, building materials, textiles, leather, agricultural products and foodstuffs PÜHRINGER, Josef, Dr. (SE) 1985-08-28 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES FABP2, FABP4, GUSB APAF1 249/4885TDP2 2915/4885CDC25B 1966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.