SCHEMBL11279744

SCHEMBL11279744

CC(Oc1ccccc1)(Oc1ccccc1)C(N)=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.50
MAPT P10636 3/20 0.50
PARP10 Q53GL7 2/20 0.42
PPARG P37231 5/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
ATM Q13315 1/20 0.41
PPARA Q07869 5/20 0.40
MEN1 O00255 4/20 0.40
CYP3A4 P08684 2/20 0.40
CYP2C19 P33261 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
CTNNB1 P35222 1/20 0.40
ALDH1A1 P00352 2/20 0.38
HSD11B1 P28845 1/20 0.38
HSD11B2 P80365 1/20 0.38
POLB P06746 1/20 0.38
PARP1 P09874 1/20 0.38
TSHR P16473 1/20 0.38
RECQL P46063 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9731099 0.84 TSHR (0.40) KMT2AMAPTPARP10PPARGL3MBTL1
SCHEMBL2822682 0.83 PPARA (0.54) KMT2AMAPTPARP10PPARGPPARA
SCHEMBL1538043 0.83 PPARA (0.47) KMT2AMAPTPPARGL3MBTL1ATM
SCHEMBL11513547 0.81 L3MBTL1 (0.42) KMT2AMAPTPPARGL3MBTL1ATM
Water SCHEMBL28074674 0.81 PPARA (0.46) KMT2AMAPTPPARGL3MBTL1ATM
SCHEMBL9736278 0.80 MAPT (0.47) KMT2AMAPTPARP10PPARGL3MBTL1
SCHEMBL27757832 0.79 MAPT (0.55) KMT2AMAPTPARP10PPARGPPARA
SCHEMBL4651825 0.78 PPARG (0.43) KMT2AMAPTPPARGL3MBTL1ATM
SCHEMBL11512906 0.78 CES1 (0.47) MAPTPPARGL3MBTL1ATMALDH1A1
SCHEMBL10198566 0.77 PPARG (0.57) KMT2AMAPTPARP10PPARGL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0011802-B1 PHENOXY-PHENOXY-PROPIONIC ACID AMIDES, PROCESSES FOR THEIR PREPARATION, HERBICIDAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN CONTROLLING THE GROWTH OF WEEDS HOECHST AKTIENGESELLSCHAFT (DE) 1982-09-15 EP claimed
EP-0011802-A1 Phenoxy-phenoxy-propionic acid amides, processes for their preparation, herbicidal compositions containing them and their use in controlling the growth of weeds HOECHST AKTIENGESELLSCHAFT (DE) 1980-06-11 EP disclosed
EP-0011802-A1 Phenoxy-phenoxy-propionic acid amides, processes for their preparation, herbicidal compositions containing them and their use in controlling the growth of weeds HOECHST AKTIENGESELLSCHAFT (DE) 1980-06-11 EP disclosed