SCHEMBL5587983

SCHEMBL5587983

CC1=CC(C2CCCCC2)=C(C)C(=O)C1=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APLNR P35414 2/20 0.38
PTPN1 P18031 2/20 0.35
PTPRC P08575 1/20 0.35
PTPRF P10586 1/20 0.35
CDC25B P30305 1/20 0.35
NR1I2 O75469 1/20 0.34
KDM4B O94953 1/20 0.34
CHRM1 P11229 1/20 0.34
TBXA2R P21731 1/20 0.34
ADRA1A P35348 1/20 0.34
DOHH Q9BU89 1/20 0.34
PTGS2 P35354 6/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
PTGS1 P23219 1/20 0.33
JAK2 O60674 2/20 0.33
JAK1 P23458 2/20 0.33
TYK2 P29597 2/20 0.33
JAK3 P52333 2/20 0.33
DAO P14920 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11279790 0.72 APLNR (0.40) APLNRPTPN1PTPRCPTPRFCDC25B
SCHEMBL30770641 0.69 MAOA (0.50) APLNRPTPN1PTPRCPTPRFCDC25B
SCHEMBL30770716 0.69 MAOA (0.50) APLNRPTPN1PTPRCPTPRFCDC25B
SCHEMBL19386509 0.69 PTPN1 (0.46) APLNRPTPN1PTPRCPTPRFCDC25B
SCHEMBL17969772 0.68 PTPN1 (0.41) APLNRPTPN1PTPRCPTPRFCDC25B
SCHEMBL32665597 0.67 MAOA (0.52) APLNRPTPN1PTPRCPTPRFCDC25B
SCHEMBL31495256 0.63 PTPN1 (0.47) APLNRPTPN1PTPRCPTPRFCDC25B
SCHEMBL10782026 0.63 MAOA (0.52) APLNRPTPN1PTPRCPTPRFCDC25B
SCHEMBL30770696 0.63 MAOA (0.52) APLNRPTPN1PTPRCPTPRFCDC25B
SCHEMBL21652144 0.61 PTPN1 (0.42) APLNRPTPN1PTPRCPTPRFCDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247687-B2 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-07-24 US disclosed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP disclosed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 US disclosed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP disclosed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization MLX, LOX, LMTK3 APLNR 4033/4885PTPN1 4679/4885PTPRC 4702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.