Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28115619 | 0.83 | MAPT (0.43) | HTR1ADRD2SIGMAR1TAAR1MAPT | |
| SCHEMBL28115961 | 0.77 | ALDH1A1 (0.41) | MAPTLMNATLR8MEN1HTT | |
| SCHEMBL31548632 | 0.73 | NPC1 (0.33) | SMN1; SMN2 | |
| SCHEMBL28094721 | 0.70 | MEN1 (0.36) | DRD2SIGMAR1MAPTMEN1KMT2A | |
| SCHEMBL28115806 | 0.69 | MEN1 (0.33) | MAPTMEN1KMT2A | |
| SCHEMBL21864339 | 0.67 | SMN1; SMN2 (0.38) | DRD2SIGMAR1SMN1; SMN2MAPTLMNA | |
| SCHEMBL31548634 | 0.67 | SIGMAR1 (0.44) | HTR1ADRD2SIGMAR1L3MBTL1 | |
| Phenethylamine SCHEMBL22472091 | 0.66 | HTR2A (0.80) | SMN1; SMN2TAAR1CYP2A6HTR2ALOXL2 | |
| Propylamine SCHEMBL27818094 | 0.66 | HTR2A (0.64) | SIGMAR1SMN1; SMN2TAAR1CYP2A6HTR2A | |
| Iodide SCHEMBL27085276 | 0.66 | NPC1 (0.37) | DRD2SIGMAR1SMN1; SMN2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338453-A | Aminoalkyl-1,2,4-triazoles | THE UPJOHN COMPANY (US) | 1982-07-06 | — | — | US | disclosed |