SCHEMBL11280210

SCHEMBL11280210

O=C(OCC1CCC=CO1)C1CC1(Cl)Cl

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4304520 0.79 TP53 (0.37) TP53CYP3A4LMNA
SCHEMBL8428847 0.75 ALDH1A1 (0.44) ALDH1A1LMNA
SCHEMBL260743 0.75 NLRP3 (0.36) ALDH1A1TP53CYP3A4LMNA
SCHEMBL259449 0.75 NLRP3 (0.36) ALDH1A1TP53CYP3A4LMNA
SCHEMBL11640528 0.73 LMNA (0.34) ALDH1A1LMNA
SCHEMBL8429838 0.73 LMNA (0.47) ALDH1A1LMNA
SCHEMBL18570723 0.73 LMNA (0.51) ALDH1A1LMNA
SCHEMBL11280208 0.72 ALDH1A1 (0.37) ALDH1A1L3MBTL1TP53CYP3A4
SCHEMBL18025586 0.72 TP53 (0.35) TP53CYP3A4LMNA
SCHEMBL1871684 0.71 ALDH1A1 (0.57) ALDH1A1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4358459-A Cyclopropane carboxylic acid and process for their production and use DEGUSSA AKTIENGESELLSCHAFT (DE) 1982-11-09 US disclosed