Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22874143 | 0.78 | APP (0.56) | APPTSHRGAAOPRD1OPRK1 | |
| SCHEMBL21581202 | 0.77 | OPRD1 (0.63) | APPTSHROPRD1OPRK1OPRM1 | |
| SCHEMBL7768912 | 0.76 | OPRM1 (0.46) | APPTSHRGAAOPRM1CYP1A2 | |
| SCHEMBL11264109 | 0.75 | OPRM1 (0.55) | APPOPRD1OPRK1OPRM1LMNA | |
| SCHEMBL8122193 | 0.75 | OPRD1 (0.53) | APPTSHRGAAOPRD1OPRK1 | |
| SCHEMBL20004190 | 0.74 | HSD11B1 (0.60) | APPTSHRGAAOPRD1OPRK1 | |
| SCHEMBL17886656 | 0.73 | TSHR (0.54) | TSHROPRD1OPRK1KDM4E | |
| SCHEMBL20004189 | 0.73 | APP (0.54) | APPTSHRGAAOPRD1OPRK1 | |
| SCHEMBL3278422 | 0.72 | CA12 (0.56) | APPTSHROPRD1OPRK1ALDH1A1 | |
| SCHEMBL11159629 | 0.72 | APP (0.55) | APPTSHRGAAOPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321379-A | NEUROLEPTIC AGENTS AND ANALGESICS | AMERICAN CYANAMID COMPANY (US) | 1982-03-23 | — | — | US | disclosed |