Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9194236 | 0.88 | OPRM1 (0.55) | OPRM1OPRD1OPRK1KCNH2SLC22A1 | |
| SCHEMBL9316412 | 0.85 | SMN1; SMN2 (0.56) | OPRM1OPRD1OPRK1KCNH2SLC22A1 | |
| SCHEMBL12194704 | 0.80 | KCNA3 (0.59) | OPRM1OPRD1OPRK1KCNH2SLC22A1 | |
| SCHEMBL22874143 | 0.80 | APP (0.56) | OPRM1OPRD1OPRK1KCNH2SLC22A1 | |
| SCHEMBL21581202 | 0.79 | OPRD1 (0.63) | OPRM1OPRD1OPRK1KCNH2SLC22A1 | |
| SCHEMBL2468907 | 0.79 | ALDH1A1 (0.60) | OPRM1OPRD1OPRK1KCNH2SLC22A1 | |
| SCHEMBL10925058 | 0.77 | OPRM1 (0.54) | OPRM1OPRD1OPRK1KCNH2SLC22A1 | |
| SCHEMBL20004190 | 0.76 | HSD11B1 (0.60) | OPRM1OPRD1OPRK1KCNH2SLC22A1 | |
| SCHEMBL16130068 | 0.75 | OPRM1 (0.67) | OPRM1OPRD1OPRK1KCNH2SLC22A1 | |
| SCHEMBL11280783 | 0.75 | APP (0.49) | OPRM1OPRD1OPRK1KCNH2SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321379-A | NEUROLEPTIC AGENTS AND ANALGESICS | AMERICAN CYANAMID COMPANY (US) | 1982-03-23 | — | — | US | disclosed |