Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11983219 | 0.86 | KDM4E (0.60) | SERPINE1KDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL11983190 | 0.84 | CFTR (0.53) | SERPINE1KDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL11284523 | 0.82 | KDM4E (0.50) | SERPINE1KDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL11280137 | 0.82 | EGFR (0.56) | SERPINE1KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL11285157 | 0.81 | EGFR (0.49) | SERPINE1KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL11292150 | 0.81 | KDM4E (0.50) | SERPINE1KDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL11291470 | 0.80 | ADORA3 (0.55) | SERPINE1KDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL11983218 | 0.80 | SERPINE1 (0.51) | SERPINE1KDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL11282857 | 0.80 | ROCK2 (0.47) | SERPINE1KDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL11983214 | 0.80 | L3MBTL1 (0.57) | SERPINE1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0059698-A1 | Heterocyclic carboxamides, compositions containing such compounds, processes for their preparation and methods of treatment therewith | AB LEO (SE) | 1982-09-08 | — | — | EP | disclosed |