Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 5/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MARS1 | P56192 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1260378 | 0.93 | CNR1 (0.49) | SRD5A2CNR1HSD11B1MEN1KMT2A | |
| SCHEMBL1258893 | 0.86 | MARS1 (0.52) | SRD5A2CNR1MEN1KMT2AMAPT | |
| SCHEMBL1986082 | 0.83 | MAPT (0.47) | ESR1MAPTSMN1; SMN2POLB | |
| SCHEMBL1260411 | 0.81 | CNR1 (0.43) | CNR1HSD11B1KMT2A | |
| SCHEMBL2906434 | 0.81 | HSD11B1 (0.47) | CNR1HSD11B1 | |
| SCHEMBL1985672 | 0.81 | PRKAB2 (0.47) | SRD5A2CNR1MARS1 | |
| SCHEMBL1259826 | 0.76 | CYP2C9 (0.42) | CNR1CYP2C9 | |
| SCHEMBL1127886 | 0.75 | CNR1 (0.55) | CNR1 | |
| SCHEMBL1127889 | 0.74 | CNR1 (0.40) | ESR1CNR1 | |
| SCHEMBL1128121 | 0.73 | CNR1 (0.56) | CNR1MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383666-B2 | Pyrrole derivatives, preparation of same and therapeutic application thereof | SANOFI (FR) | 2013-02-26 | — | — | US | disclosed |
| EP-2283008-B1 | PYRROLE DERIVATIVES, PREPARATION OF SAME AND THERAPEUTIC APPLICATION THEREOF | SANOFI SA (FR) | 2011-11-02 | — | — | EP | disclosed |