Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11290216 | 0.89 | PMP22 (0.48) | HIF1ALMNAADRB2ADRB1CYP1A2 | |
| SCHEMBL11281999 | 0.87 | HIF1A (0.52) | HIF1AALDH1A1LMNACYP3A4ADRB2 | |
| SCHEMBL11288212 | 0.85 | LMNA (0.46) | HIF1AALDH1A1LMNACYP3A4ADRB2 | |
| SCHEMBL11279956 | 0.85 | HIF1A (0.54) | HIF1AALDH1A1LMNACYP3A4ADRB2 | |
| SCHEMBL11280679 | 0.84 | ADRB2 (0.39) | HIF1AALDH1A1LMNACYP3A4ADRB2 | |
| SCHEMBL11289635 | 0.84 | ADRB2 (0.59) | HIF1ALMNACYP3A4ADRB2ADRB1 | |
| SCHEMBL11283530 | 0.84 | ADRB2 (0.52) | HIF1AALDH1A1LMNAADRB2ADRB1 | |
| SCHEMBL11285938 | 0.83 | PMP22 (0.47) | HIF1ALMNAADRB2ADRB1CYP1A2 | |
| SCHEMBL11287951 | 0.83 | ADRB2 (0.52) | HIF1AADRB2ADRB1CYP1A2CYP2D6 | |
| SCHEMBL11284504 | 0.80 | ADRB2 (0.49) | HIF1AALDH1A1LMNACYP3A4ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |