Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 9/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11288231 | 0.85 | MAPT (0.36) | ADRB2ADRB1ADRB3RXFP1LMNA | |
| SCHEMBL11281997 | 0.84 | HIF1A (0.51) | ADRB2ADRB1ADRB3ALDH1A1LMNA | |
| SCHEMBL11290216 | 0.82 | PMP22 (0.48) | ADRB2ADRB1ADRB3LMNAHIF1A | |
| SCHEMBL11280670 | 0.81 | RXFP1 (0.37) | ADRB2ADRB1ADRB3RXFP1ALDH1A1 | |
| SCHEMBL11280676 | 0.80 | ALDH1A1 (0.36) | ADRB2ADRB1ADRB3ALDH1A1LMNA | |
| SCHEMBL11428882 | 0.79 | CCR5 (0.41) | ADRB2ADRB1ADRB3ALDH1A1LMNA | |
| SCHEMBL11289571 | 0.77 | ALDH1A1 (0.45) | ADRB2ADRB1ADRB3ALDH1A1LMNA | |
| SCHEMBL11283530 | 0.77 | ADRB2 (0.52) | ADRB2ADRB1ADRB3RXFP1ALDH1A1 | |
| SCHEMBL11285938 | 0.76 | PMP22 (0.47) | ADRB2ADRB1ADRB3LMNAHIF1A | |
| SCHEMBL11287951 | 0.76 | ADRB2 (0.52) | ADRB2ADRB1ADRB3HIF1ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |