Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SCN4A | P35499 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.31 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334709 | 0.77 | LMNA (0.47) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL11741326 | 0.75 | P2RX4 (0.42) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL5803934 | 0.74 | P2RX4 (0.33) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL5804812 | 0.69 | SMN1; SMN2 (0.48) | LMNATSHRSMN1; SMN2GAA | |
| SCHEMBL8423853 | 0.68 | P2RX4 (0.35) | P2RX4PTBP1P2RX1P2RX3SMN1; SMN2 | |
| SCHEMBL11667029 | 0.68 | LMNA (0.33) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL11882961 | 0.67 | LMNA (0.31) | LMNATSHRMAPK1SCN4ASCN5A | |
| SCHEMBL3760901 | 0.65 | CES2 (0.31) | P2RX4NPSR1GAA | |
| SCHEMBL7339454 | 0.65 | LMNA (0.40) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL6610178 | 0.65 | LMNA (0.40) | P2RX4LMNATSHRMAPK1SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4347364-A | INTERMEDIATES THEREFOR | HOFFMANN-LA ROCHE INC. (US) | 1982-08-31 | — | — | US | disclosed |
| US-4307237-A | ANTICONVULSANTS, SEDATIVES, MUSCLE RELAXANTS | HOFFMANN-LA ROCHE INC. (US) | 1981-12-22 | — | — | US | disclosed |