Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907598 | 0.84 | MEN1 (0.48) | TTRMEN1KMT2AHSPB1ALDH1A1 | |
| SCHEMBL11583868 | 0.84 | XDH (0.49) | TTRMEN1KMT2AHSPB1ALDH1A1 | |
| SCHEMBL9638881 | 0.83 | ALDH1A1 (0.50) | TTRMEN1KMT2AHSPB1ALDH1A1 | |
| SCHEMBL10788442 | 0.82 | TTR (0.49) | TTRMEN1KMT2AHSPB1ALDH1A1 | |
| SCHEMBL16540468 | 0.80 | TTR (0.47) | TTRMEN1KMT2AHSPB1ALDH1A1 | |
| SCHEMBL29749825 | 0.80 | PDK1 (0.58) | TTRMEN1KMT2AHSPB1ALDH1A1 | |
| SCHEMBL6809251 | 0.80 | PDK1 (0.58) | TTRMEN1KMT2AHSPB1ALDH1A1 | |
| SCHEMBL5802973 | 0.79 | MAPT (0.52) | TTRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3911316 | 0.79 | TTR (0.44) | TTRMEN1KMT2AHSPB1ALDH1A1 | |
| SCHEMBL13681704 | 0.78 | MAPT (0.54) | TTRMEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329504-A | COUPLERS FOR DYES, HAIR DYES | SOCIETE ANONYME DITE: L'OREAL (FR) | 1982-05-11 | — | — | US | disclosed |
| US-4259261-A | OXIDATION COLOR DYES FOR HAIR | L'OREAL (FR) | 1981-03-31 | — | — | US | disclosed |