Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 3/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | TACR1 | P25103 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18576677 | 0.89 | CTRB1 (0.67) | CTRB1CA12CA1CA2CA9 | |
| SCHEMBL2353282 | 0.89 | CTRB1 (0.67) | CTRB1CA12CA1CA2CA9 | |
| SCHEMBL223417 | 0.87 | CTRB1 (0.53) | CTRB1CA12CA1CA2CA9 | |
| SCHEMBL18328210 | 0.83 | CTRB1 (0.74) | CTRB1SYKATMCTSKTACR1 | |
| SCHEMBL18320645 | 0.83 | CTRB1 (0.74) | CTRB1SYKATMCTSKTACR1 | |
| SCHEMBL2749553 | 0.82 | PPARA (0.53) | CTRB1CA12CA1CA2CA9 | |
| SCHEMBL2102910 | 0.82 | CASP1 (0.52) | CTRB1CA12CA1CA2CA9 | |
| SCHEMBL31089911 | 0.82 | CA2 (0.54) | CTRB1CA12CA1CA2CA9 | |
| SCHEMBL30629995 | 0.82 | CA2 (0.54) | CTRB1CA12CA1CA2CA9 | |
| SCHEMBL19136379 | 0.82 | CA2 (0.54) | CTRB1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048532-A2 | Sultines; a process for producing these; a process for producing sulfoxides; a process for producing sparsomycin and related compounds | Stichting Research en Techniek van de Katholieke Universiteit (NL) | 1982-03-31 | — | — | EP | disclosed |