Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | TOP2A | P11388 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.36 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.36 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.36 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11287417 | 1.00 | ALOX15 (0.45) | ALOX15TOP2AALDH1A1LMNACYP3A4 | |
| SCHEMBL11288390 | 1.00 | ALOX15 (0.45) | ALOX15TOP2AALDH1A1LMNACYP3A4 | |
| SCHEMBL11290106 | 0.90 | TBXA2R (0.40) | ALOX15TOP2ACA2NPC1RAB9A | |
| SCHEMBL11292338 | 0.87 | ALOX15 (0.48) | ALOX15TOP2ATRPV1POLMPOLK | |
| SCHEMBL11277096 | 0.87 | ALOX15 (0.48) | ALOX15TOP2ATRPV1POLMPOLK | |
| SCHEMBL11283818 | 0.85 | LMNA (0.48) | ALOX15TOP2AALDH1A1LMNACYP3A4 | |
| SCHEMBL11288392 | 0.85 | LMNA (0.48) | ALOX15TOP2AALDH1A1LMNACYP3A4 | |
| SCHEMBL11287420 | 0.85 | LMNA (0.48) | ALOX15TOP2AALDH1A1LMNACYP3A4 | |
| SCHEMBL11284347 | 0.84 | FAAH (0.38) | ALOX15ALDH1A1LMNAPOLMPOLK | |
| SCHEMBL11278379 | 0.83 | LMNA (0.52) | ALOX15TOP2AALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |