Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11284349 | 0.90 | FAAH (0.39) | FAAHMAPTALDH1A1MEN1HPGD | |
| SCHEMBL11289778 | 0.88 | FAAH (0.39) | FAAHMAPTALDH1A1MEN1HPGD | |
| SCHEMBL11283807 | 0.84 | ALOX15 (0.45) | ALDH1A1KMT2ALMNANPC1ALOX15 | |
| SCHEMBL11287417 | 0.84 | ALOX15 (0.45) | ALDH1A1KMT2ALMNANPC1ALOX15 | |
| SCHEMBL11288390 | 0.84 | ALOX15 (0.45) | ALDH1A1KMT2ALMNANPC1ALOX15 | |
| SCHEMBL11288888 | 0.83 | FAAH (0.43) | FAAHMAPTALDH1A1MEN1HPGD | |
| Alcohol SCHEMBL11284343 | 0.78 | ALOX15 (0.38) | FAAHMAPTALDH1A1MEN1HPGD | |
| SCHEMBL11288886 | 0.77 | ALOX15 (0.43) | FAAHMAPTALDH1A1MEN1HPGD | |
| SCHEMBL11290106 | 0.75 | TBXA2R (0.40) | MEN1KMT2ANPC1ALOX15 | |
| SCHEMBL11279271 | 0.75 | ALDH1A1 (0.47) | ALDH1A1LMNAALOX15POLMPOLK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |