Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557849 | 0.86 | KDM4E (0.48) | PTGS2MEN1ALDH1A1KMT2A | |
| SCHEMBL11292140 | 0.75 | KDM4E (0.38) | MEN1ALDH1A1KMT2A | |
| SCHEMBL9185831 | 0.74 | MEN1 (0.49) | MEN1ALDH1A1KMT2A | |
| SCHEMBL2485933 | 0.72 | ALDH1A1 (0.47) | MEN1ALDH1A1KMT2A | |
| SCHEMBL9269032 | 0.72 | CSF1R (0.42) | PTGS2MEN1ALDH1A1KMT2ACSF1R | |
| SCHEMBL7868368 | 0.72 | PTGS2 (0.48) | PTGS2 | |
| SCHEMBL11283957 | 0.71 | KMT2A (0.43) | MEN1ALDH1A1KMT2A | |
| SCHEMBL11288352 | 0.71 | CSF1R (0.42) | PTGS2MEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11983217 | 0.71 | KDM4E (0.50) | PTGS2MEN1ALDH1A1KMT2A | |
| SCHEMBL11983224 | 0.70 | TP53 (0.47) | PTGS2MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0059698-A1 | Heterocyclic carboxamides, compositions containing such compounds, processes for their preparation and methods of treatment therewith | AB LEO (SE) | 1982-09-08 | — | — | EP | disclosed |