Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9270496 | 0.82 | MEN1 (0.37) | MEN1KMT2AKDM4EGSK3B | |
| SCHEMBL9270253 | 0.81 | ALDH1A1 (0.43) | CSF1RPTGS2ALDH1A1MAPTMEN1 | |
| SCHEMBL9266252 | 0.76 | PTGS2 (0.35) | CSF1RPTGS2ALDH1A1MAPTMEN1 | |
| SCHEMBL9270566 | 0.76 | PRNP (0.36) | CSF1RMEN1KMT2AMAP4K4PIM1 | |
| SCHEMBL9268660 | 0.75 | CNR1 (0.39) | PTGS2MAPTADRA2AADRA2BADRA2C | |
| SCHEMBL11284238 | 0.72 | PTGS2 (0.50) | CSF1RPTGS2ALDH1A1MEN1KMT2A | |
| SCHEMBL6991966 | 0.71 | MEN1 (0.52) | CSF1RALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11288352 | 0.69 | CSF1R (0.42) | CSF1RPTGS2ALDH1A1MAPTMEN1 | |
| SCHEMBL11983224 | 0.69 | TP53 (0.47) | PTGS2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9269029 | 0.67 | MEN1 (0.46) | ALDH1A1MEN1KMT2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995024395-A1 | QUINOLINE DERIVATIVES AS IMMUNOMODULATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-14 | — | — | WO | disclosed |