Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | USP8 | P40818 | 1/20 | 0.33 |
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | BRD1 | O95696 | 1/20 | 0.32 |
| ▸ | TAF1 | P21675 | 1/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278160 | 0.91 | CASP3 (0.43) | CASP3GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL11287708 | 0.84 | ALDH1A1 (0.36) | PGRUSP8USP7LMNAMAPT | |
| SCHEMBL11285155 | 0.79 | PGR (0.33) | CASP3PGRUSP8USP7LMNA | |
| SCHEMBL11285526 | 0.76 | CASP3 (0.35) | CASP3PGRLMNAMAPTALDH1A1 | |
| SCHEMBL11287713 | 0.76 | PGR (0.32) | CASP3PGRUSP8USP7LMNA | |
| SCHEMBL11285533 | 0.76 | CASP3 (0.44) | CASP3LMNATP53MAPTALDH1A1 | |
| SCHEMBL11280457 | 0.74 | CHRM2 (0.35) | CASP3GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL11278169 | 0.71 | CASP3 (0.36) | CASP3 | |
| SCHEMBL11285530 | 0.68 | CASP3 (0.34) | CASP3GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL11285502 | 0.68 | NR1H2 (0.42) | CASP3GABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4349618-A | 5-DIPHENYLMETHYLENE- OR 5-(FLUOREN-9-YLIDENE) THIOBARBITURIC ACID AND DERIVATIVES AS SENSITIZERS FOR N-VVINYLCARBAZOLE POLYMERS; ELECTROPHORESIS | FUJI PHOTO FILM CO., LTD. (JP) | 1982-09-14 | — | — | US | disclosed |