Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 12/20 | 0.60 |
| ▸ | CES1 | P23141 | 11/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.42 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29524968 | 0.79 | P4HA1 (0.64) | LDHAHCAR3P4HA1P4HTMALDH1A1 | |
| SCHEMBL185991 | 0.79 | P4HA1 (0.64) | LDHAHCAR3P4HA1P4HTMALDH1A1 | |
| SCHEMBL1195835 | 0.78 | CES2 (1.00) | CES2CES1RAB9AALDH1A1 | |
| Benzil SCHEMBL4957522 | 0.78 | CES2 (1.00) | CES2CES1RAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9162215 | 0.77 | P4HA1 (0.61) | LDHAHCAR3P4HA1P4HTMALDH1A1 | |
| Benzil SCHEMBL2156589 | 0.75 | CES2 (1.00) | CES2CES1RAB9AKDM4EALDH1A1 | |
| Benzil SCHEMBL7142843 | 0.75 | CES2 (1.00) | CES2CES1RAB9AKDM4EALDH1A1 | |
| Benzil SCHEMBL28475956 | 0.75 | CES2 (1.00) | CES2CES1RAB9AKDM4EALDH1A1 | |
| Benzil SCHEMBL9517636 | 0.75 | CES2 (1.00) | CES2CES1RAB9AKDM4EALDH1A1 | |
| Benzil SCHEMBL66 | 0.75 | CES2 (1.00) | CES2CES1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046451-A2 | Diaryl-imidazole compounds, methods for their preparation, pharmaceutical drugs containing them and their use | CIBA-GEIGY AG (CH) | 1982-02-24 | — | — | EP | disclosed |